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ChemInform Abstract: Synthesis of Small and Medium Sized 2,2-Disubstituted Lactams via the “ Intramolecular” Three Component Ugi Reaction.

✍ Scribed by G. C. B. HARRIMAN


Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


Synthesis of Small and Medium Sized 2,2-Disubstituted Lactams via the " Intramolecular" Three Component Ugi Reaction. -Tethered keto-acids undergo an intramolecular three-component Ugi reaction with a variety of primary amines and isocyanates to form five-to eight-membered lactams in good yields. -(HARRIMAN, G.


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