## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Liquid-phase combinatorial synthesis: In search of small-molecule enzyme mimics
β Scribed by Anthony M. Vandersteen; Hyunsoo Han; Kim D. Janda
- Book ID
- 105287300
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 655 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1381-1991
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π SIMILAR VOLUMES
The first synthesis of a combinatorial library using double combinatorial chemistry is presented. Coupling of unprotected Fmoc-tyrosine to the solid support was followed by Mitsunobu O-alkylation. Introduction of a diacid linker yields a system in which the double combinatorial step can be demonstra
Domino reactions are highly efficient processes that allow the synthesis of complex molecules starting from simple substrates, in a straightforward fashion. The transformations are extremely useful for the design of small-molecule libraries by combinatorial chemistry if multicomponent domino reactio