The first synthesis of a combinatorial library using double combinatorial chemistry is presented. Coupling of unprotected Fmoc-tyrosine to the solid support was followed by Mitsunobu O-alkylation. Introduction of a diacid linker yields a system in which the double combinatorial step can be demonstra
โฆ LIBER โฆ
"Analogous" Organic Synthesis of Small-Compound Libraries: Validation of Combinatorial Chemistry in Small-Molecule Synthesis
โ Scribed by Chen, Chixu; Randall, Lisa A. Ahlberg; Miller, R. Bryan; Jones, A. Daniel; Kurth, Mark J.
- Book ID
- 121238142
- Publisher
- American Chemical Society
- Year
- 1994
- Tongue
- English
- Weight
- 310 KB
- Volume
- 116
- Category
- Article
- ISSN
- 0002-7863
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