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Liquid Chromatography–Tandem Mass Spectrometry Analysis of 2-Amino-1-methyl-6-(4-hydroxyphenyl)imidazo[4,5- b ]pyridine in Cooked Meats

✍ Scribed by Busquets, R.; Puignou, L.; Galceran, M. T.; Wakabayashi, K.; Skog, K.


Book ID
119937929
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
206 KB
Volume
55
Category
Article
ISSN
0021-8561

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## 2-Amino -1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is the most abundant heterocyclic aromatic amine found in cooked meat. It is metabolically activated by the human cytochrome P450 enzymes to form the carcinogenic metabolite N 2 -OH-PhIP. PhIP has been found to induce tumors in rats and is