## Abstract 2βaminoβ1βmethylβ6βphenylimidazo[4,5β__b__]pyridine (PhIP) is the most abundant heterocyclic amine derived from food, possibly involved in human carcinogenesis. We evaluated the formation of PhIPβDNA adducts in lymphocytes from 76 incident colorectal cancer patients likely to be exposed
Formation of protein adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in cooked foods
β Scribed by Hiroyuki Kataoka; Mina Miyake; Sachiko Nishioka; Tomoko Matsumoto; Keita Saito; Kurie Mitani
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 339 KB
- Volume
- 54
- Category
- Article
- ISSN
- 1613-4125
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## Abstract magnified image Synthesis of 2βaminoβ1βmethylβ6βphenylimidazo[4,5β__b__]pyridine (PhIP), three structural isomers, and two desphenyl PhIP congeners has been carried out. Mutagenic potency was evaluated using __S. typhimurium__ strain TA98 in the Ames test. Mutagenic potency increased i
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