Thermospray liquid chromatography/mass spectrometry using a double-focusing magnetic sector mass spectrometer has been studied. The quality of the thermospray mass spectra were often a function of the solvent mixture used, and use of gradients affected the quality of some thermospray mass spectra. H
Liquid chromatography-mass spectrometry. II—continuous monitoring
✍ Scribed by Patrick Arpino; M. A. Baldwin; F. W. McLafferty
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 244 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1076-5174
No coin nor oath required. For personal study only.
✦ Synopsis
Monitoring of solutes eluted from a liquid chromatograph is possible by continuous introduction of the effluent solution into the ion source of a chemical ionization mass spectrometer. Detection sensitivities in the nanogram range are possible for a wide variety of solutes and solvents. Auxiliary techniques which have proved valuable for g.c.-m.s. also appear to be applicable to I.c.m.s.
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