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Lipocortin 1 and the control of cPLA2 activity in A549 cells: Glucocorticoids block EGF stimulation of cPLA2 phosphorylation

✍ Scribed by Jamie D. Croxtall; Qam Choudhury; Simon Newman; Rod J. Flower


Book ID
115784530
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
775 KB
Volume
52
Category
Article
ISSN
0006-2952

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The release of [ 3 H] arachidonic acid (AA) and its connection with the triggering of the MAP kinase cascade were studied in the human A549 epithelial cell line upon stimulation with thapsigargin. Thapsigargin can increase AA release along with the increase of intracellular calcium concentration, ph