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Lipid-Like Nanomaterials for Simultaneous Gene Expression and Silencing In Vivo

โœ Scribed by Dong, Yizhou; Eltoukhy, Ahmed A.; Alabi, Christopher A.; Khan, Omar F.; Veiseh, Omid; Dorkin, J. Robert; Sirirungruang, Sasilada; Yin, Hao; Tang, Benjamin C.; Pelet, Jeisa M.; Chen, Delai; Gu, Zhen; Xue, Yuan; Langer, Robert; Anderson, Daniel G.

Book ID
121816281
Publisher
Wiley (John Wiley & Sons)
Year
2014
Tongue
English
Weight
858 KB
Volume
3
Category
Article
ISSN
2192-2640

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## Abstract A method to achieve simultaneous water and lipid suppression is described. The key feature of the new dual suppression technique is the use of the wellโ€known hyperbolic secant (HS) waveform as a 90ยฐ saturation pulse. Two HS pulses with opposite frequency offsets are employed either sequ