๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Lipid composition of myelin in multiple sclerosis

โœ Scribed by Mona E. Fewster; H. Hirono; J. F. Mead

Publisher
Springer
Year
1976
Tongue
English
Weight
757 KB
Volume
213
Category
Article
ISSN
0340-5354

No coin nor oath required. For personal study only.

โœฆ Synopsis

Myelin was isolated from histologically normal white matter and plaques from MS patients and from white matter of neurologically normal controls. No difference was found in the total lipid content. There were no detectable deficits in MS myelin of phosphoglycerides, plasmalogens or sphingolipids. Gangliosides and lysolecithin were not detected. Analysis of the fatty aldehyde composition of the phosphoglycerides and the fatty acid composition of the cholesteryl esters, phosphoglycerides and sphingolipids did not show any differences between the normal and MS myelin.

๐Ÿ“œ SIMILAR VOLUMES

Multiple sclerosis: From a myelin point
Multiple sclerosis: From a myelin point of view
โœ G.L. Boccaccio; L. Steinman ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 870 KB

Multiple sclerosis (MS) is a demyelinating disease during which an autoimmune reaction is directed against oligodendrocytes. Alterations of normal myelin structure or oligodendrocyte metabolism may be primary events that influence the susceptibility to MS. Once triggered, the immune system attacks a