Lipase catalyzed transesterification of methyl acetoacetate with n-butanol
β Scribed by Ganapati D. Yadav; Piyush S. Lathi
- Book ID
- 113803878
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 275 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1381-1177
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## Abstract The transesterification of methyl acetate and __n__βbutanol catalyzed by cationβexchange resin, NKCβ9, was studied in this work to obtain the reaction kinetics. The experiments were carried out in a stirred batch reactor at different temperatures (328.15, 333.15, 338.15, 343.15, 345.15
The present research introduces the highly (S)-selective (E>>100) acylation at the secondary ring nitrogen of methyl pipecolinate as a novel resolution method with Candida antarctica lipase A. Catalysis by lipase B leads to reactions at the methyl ester function of the substrate in an almost non-ena