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Lipase-catalyzed kinetic resolutions of racemic β- and γ-thiolactones

✍ Scribed by Bum-Yeol Hwang; Hee Bong Lee; Young Gyu Kim; Byung-Gee Kim


Book ID
113804078
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
218 KB
Volume
41
Category
Article
ISSN
1381-1177

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Lipase-catalyzed kinetic resolution of r
✍ Kosei Shioji; Ayako Matsuo; Kentaro Okuma; Kaoru Nakamura; Atsuyoshi Ohno 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 60 KB

Optically active 3-, 4-, 5-, or 6-methyl substituted seven-membered lactones were prepared by Candida antarctica lipase (CAL)-catalyzed kinetic resolution of the racemic lactones. Among these lactones, only in the case of 5-methylhexanolide (R)-isomer reacts faster than the other enantiomer, while t