𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Linkage between inherited resistance to activated protein C and factor V gene mutation in venous thrombosis

✍ Scribed by B. Zöller; B. Dahlbäck

Book ID
118556856
Publisher
The Lancet
Year
1994
Tongue
English
Weight
349 KB
Volume
343
Category
Article
ISSN
0140-6736

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Activated protein C resistance and the f
Activated protein C resistance and the factor V Leiden mutation in children with thrombosis
✍ Sifontes, Maria T.; Nuss, Rachelle; Hunger, Stephen P.; Waters, Jill; Jacobson, 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 22 KB 👁 2 views

To determine the prevalence of activated protein C resistance and the factor V Leiden mutation (position 1691, arginine 506 to glutamine substitution) in children with thrombosis, plasma samples from children with thrombosis were tested for activated protein C resistance. DNA was analyzed for the fa

Detection of a common mutation in factor
Detection of a common mutation in factor V gene responsible for resistance to activated protein C causing predisposition to thrombosis
✍ A. Ferreira-Gonzalez; LM Fisher; CM Lehman; MH Langley; DH Lofland; Q Xia; NX Ng 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 119 KB 👁 1 views

Hereditary predisposition to thrombosis due to activated protein C resistance (APCR) has been attributed to a missense mutation in the factor V gene at nucleotide 1691 (G to A), causing replacement of arginine at codon 506 with glutamine. Using an RFLP-PCR assay to detect this mutation, we measured