Factor V mutations in Iranian patients with activated protein C resistance and venous thrombosis
β Scribed by Rouzbeh Chegeni; Bahram Kazemi; Abbas Hajifathali; AliAkbar Pourfathollah; Ghasem Rastegar Lari
- Book ID
- 116913429
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 108 KB
- Volume
- 119
- Category
- Article
- ISSN
- 0049-3848
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Four hundred and ninety-three consecutive patients referred for arterial or venous thrombosis were screened for congenital and acquired abnormalities of blood coagulation predisposing to thrombosis, and were compared to 341 age-and sex-matched controls. The aim of the study was to determine the prev
To determine the prevalence of activated protein C resistance and the factor V Leiden mutation (position 1691, arginine 506 to glutamine substitution) in children with thrombosis, plasma samples from children with thrombosis were tested for activated protein C resistance. DNA was analyzed for the fa