𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Linkage analysis in Spanish families with nonspecific X-linked mental retardation: Significant linkage at Xq13-q21

✍ Scribed by Badenas, Celia ;Castellv�-Bel, Sergi ;Volpini, Victor ;Jim�nez, Dolores ;S�nchez, Aurora ;Estivill, Xavier ;Mil�, Montserrat


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
115 KB
Volume
98
Category
Article
ISSN
0148-7299

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Linkage analysis in three families with
✍ Claes, S.; Gu, X. X.; Legius, E.; Lorenzetti, E.; Marynen, P.; Fryns, J. P.; Cas 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 155 KB

Nonspecific X-linked mental retardation (XLMR) is a common disorder. The number of genes involved in this condition is not known, but it is estimated to be more than 10. We present a clinical and linkage study on 3 families with XLMR. All families were analyzed using highly polymorphic markers cover

Linkage analysis in a large family with
✍ Glass, I. A. ;White, E. M. ;Pope, M. J. ;Pirrit, L. A. ;Cockburn, F. ;Connor, J. 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 629 KB

We report on a large 5-generation family with "nonspecific" X-linked mental retardation. Nine living affected males have an I& between 50 and 70 but have normal stature, facial appearance, and testicular volumes and no other abnormalities. Two obligate carrier females had borderline intellectual abi

X-linked nonspecific mental retardation
✍ des Portes, Vincent; Beldjord, Ch�rif; Chelly, Jamel; Hamel, Ben; Kremer, Hannie 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 33 KB 👁 2 views

The identification of X-linked mental retardation genes (XLMR) represents a challenge of considerable medical importance, given the reported high cumulative frequency of this heterogenous disorder, estimated at approximately 1/600 male births. Whereas pooling families is useful to fine-map genetic l

X-linked nonspecific mental retardation
✍ Gendrot, Chantal; Ronce, Nathalie; Raynaud, Martine; Ayrault, Anne-Dominique; Do 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 94 KB 👁 2 views

A genetic linkage study was performed on a large four-generation family with variable nonspecific X-linked mental retardation (MRX16), speech abnormalities, and retardation of all milestones. Significant linkage was found in the Xq28 region with loci DXS52, DXS15, BGN, and DXS1108 with maximum LOD s