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Linkage Analysis in Man by Somatic Cell Genetics

✍ Scribed by RUDDLE, FRANK H.

Book ID
109685296
Publisher
Nature Publishing Group
Year
1973
Tongue
English
Weight
631 KB
Volume
242
Category
Article
ISSN
0028-0836

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## Abstract The ability to detect or reject genetic linkage in studies of human cancer is often diminished because multiple affected relatives in a pedigree are unavailable for analysis. The observation of somatic allele loss in tumors can provide knowledge about gametic phase. Therefore, considera