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Genetic Analysis with Man–Mouse Somatic Cell Hybrids: Linkage between Human Lactate Dehydrogenase A and B and Peptidase B

✍ Scribed by RUDDLE, F. H.; CHAPMAN, V. M.; CHEN, T. R.; KLEBE, R. J.

Book ID
109674369
Publisher
Nature Publishing Group
Year
1970
Tongue
English
Weight
868 KB
Volume
227
Category
Article
ISSN
0028-0836

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Genetics of somatic mammalian cells. XV.
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✍ Carol Jones; Paul Wuthier; Fa-Ten Kao; Theodore T. Puck 📂 Article 📅 1972 🏛 John Wiley and Sons 🌐 English ⚖ 550 KB

Chincsc hamster ovary cells with a deficiency i n Serine Hydroxymethylase which produces a specific glycine auxotrophy (gly-A) were fused with human cells from a variety of sources and the resulting hybrids analyzed for human gene linkage. Of 102 hybrid clones examined 65 possessed both glyA and lac