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Linear polyethylenimine-graft-chitosan copolymers as efficient DNA/siRNA delivery vectors in vitro and in vivo

✍ Scribed by Sushil K. Tripathi; Ritu Goyal; Pradeep Kumar; Kailash C. Gupta

Book ID: 113811772
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 740 KB
Volume: 8
Category: Article
ISSN: 1549-9634
DOI: 10.1016/j.nano.2011.06.022

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## Abstract ## Background Chitosans of high molecular weights have emerged as efficient nonviral gene delivery systems, but the properties and efficiency of well‐defined low molecular weight chitosans (<5 kDa) have not been studied. We therefore characterized DNA complexes of such low molecular we