Linear amides as substance P antagonists

✍ Scribed by M. Teall; T. Harrison; J.D. Moseley; A.P. Owens; S. Sadowski; M.A. Cascieri

• Book ID: 104364621
• Publisher: Elsevier Science
• Year: 1996
• Tongue: English
• Weight: 166 KB
• Volume: 6
• Category: Article
• ISSN: 0960-894X
• DOI: 10.1016/s0960-894x(96)00280-6

✦ Synopsis

In the present study we demonstrate that an amide linking group provides an excellent template for the positioning of a benzhydryl group and a suitably functionalized aromatic ring in an orientation which allows for high affinity binding to the hNK 1 receptor.