Linear amides as substance P antagonists
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M. Teall; T. Harrison; J.D. Moseley; A.P. Owens; S. Sadowski; M.A. Cascieri
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Article
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1996
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Elsevier Science
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English
โ 166 KB
In the present study we demonstrate that an amide linking group provides an excellent template for the positioning of a benzhydryl group and a suitably functionalized aromatic ring in an orientation which allows for high affinity binding to the hNK 1 receptor.