𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Limits to the concept of solid-state stability

✍ Scribed by J. T. Carstensen; K. Danjo; S. Yoshioka; M. Uchiyama

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
296 KB
Volume
76
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Mechanisms of protein stabilization in t
Mechanisms of protein stabilization in the solid state
✍ Liuquan (Lucy) Chang; Michael J. Pikal πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 390 KB πŸ‘ 1 views

The solid state is preferred for many proteins due to their marginal stability in solution. However, even in the solid state, chemical and physical degradation can occur on the time scale of the drying process, distribution and use. This review summarizes the major degradation pathways of proteins i

Investigation of the effects of pharmace
Investigation of the effects of pharmaceutical processing upon solid-state NMR relaxation times and implications to solid-state formulation stability
✍ Joseph W. Lubach; Dawei Xu; Brigitte E. Segmuller; Eric J. Munson πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 276 KB πŸ‘ 1 views

Crystalline lactose was subjected to various forms of pharmaceutical processing including compaction, lyophilization, spray drying, and cryogrinding. (13)C cross polarization and magic-angle spinning (CPMAS) NMR spectra were acquired for bulk crystalline lactose as well as the processed samples. Sat

Kinetics of digestive enzyme stability i
Kinetics of digestive enzyme stability in solid state I: Application of weibull distribution function to solid-state enzyme inactivation
✍ Mamoru Sugiura; Masayuki Kurobe; Sumihiro Tamura; Shinichi Ikeda πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 English βš– 351 KB

The Weibull distribution function was applied to solid-state enzyme inactivation. On Weibull probability paper (within a narrow range), the plots of the accumulated inactivation ratio of each enzyme versus time regressed to a straight line. The parameters m and k, which correspond to the type and ra