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LIME mediates immunological synapse formation through activation of VAV

✍ Scribed by Myoungsun Son; Inyoung Park; Ok-Hee Lee; Inmoo Rhee; Changwon Park; Yungdae Yun


Book ID
113056104
Publisher
Korean Society for Molecular and Cellular Biology
Year
2012
Tongue
English
Weight
871 KB
Volume
33
Category
Article
ISSN
1016-8478

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## Abstract ## Objective Leflunomide, a potent disease‐modifying antirheumatic drug of the isoxazole class, exhibits antiinflammatory, antiproliferative, and immunosuppressive effects by largely unknown mechanisms, although alterations of pyrimidine synthesis have been proposed. Successful immune