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Coordination of T Cell Activation and Migration through Formation of the Immunological Synapse

✍ Scribed by MICHAEL L. DUSTIN

Book ID
111398003
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
1004 KB
Volume
987
Category
Article
ISSN
0890-6564

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An immunological synapse (IS) is formed at the interface between antigen-presenting cells and T cells, and is believed to be the structure responsible for antigen recognition and T-cell activation. However, recent imaging analyses reveal that T-cell receptor microclusters (MCs) formed prior to IS ar