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Library design for NMR-based screening

โœ Scribed by Christopher A. Lepre


Book ID
114383352
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
121 KB
Volume
6
Category
Article
ISSN
1359-6446

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๐Ÿ“œ SIMILAR VOLUMES


A Straightforward NMR-Spectroscopy-Based
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A variety of NMR-based methods have been devised to facilitate the screening of compound mixtures for components that bind protein drug targets. [1ยฑ6] The majority of these approaches have been developed in recent years, hand in hand with methods for generating libraries of compounds by combinatoria

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Screening of increasingly large chemical libraries has become the method of choice in the search for compounds that could be starting points in the pharmaceutical discovery process. As the process matures, the requirements on the compounds that constitute such libraries are becoming more stringent.