Library design for NMR-based screening
โ Scribed by Christopher A. Lepre
- Book ID
- 114383352
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 121 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1359-6446
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A variety of NMR-based methods have been devised to facilitate the screening of compound mixtures for components that bind protein drug targets. [1ยฑ6] The majority of these approaches have been developed in recent years, hand in hand with methods for generating libraries of compounds by combinatoria
Screening of increasingly large chemical libraries has become the method of choice in the search for compounds that could be starting points in the pharmaceutical discovery process. As the process matures, the requirements on the compounds that constitute such libraries are becoming more stringent.