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A Straightforward NMR-Spectroscopy-Based Method for Rapid Library Screening

✍ Scribed by Aloysius H. Siriwardena; Fang Tian; Schroder Noble; James H. Prestegard

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
129 KB
Volume
41
Category
Article
ISSN
0044-8249

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πŸ“œ SIMILAR VOLUMES

A Straightforward NMR-Spectroscopy-Based
A Straightforward NMR-Spectroscopy-Based Method for Rapid Library Screening
✍ Aloysius H. Siriwardena; Fang Tian; Schroder Noble; James H. Prestegard πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 129 KB

A variety of NMR-based methods have been devised to facilitate the screening of compound mixtures for components that bind protein drug targets. [1Β±6] The majority of these approaches have been developed in recent years, hand in hand with methods for generating libraries of compounds by combinatoria

Evaluation of a capillary electrophoreti
Evaluation of a capillary electrophoretic method for rapid screening of single-component combinatory libraries
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The potential utility of capillary electrophoresis CE as an analysis and biological assay method for rapid screening of single-component combinatory libraries is demonstrated by mimicking a 5 = 5 drug matrix. Twenty-five com-Ε½ . pounds some drugs, vitamins, metabolites, etc. that include biotin are