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Lesions of midbrain raphe in the rat: Effect on level of biogenic amines in forebrain and spinal cord

✍ Scribed by E. Giacalone; W. Kostowski

Book ID
117196263
Publisher
Elsevier Science
Year
1969
Weight
280 KB
Volume
1
Category
Article
ISSN
0031-6989

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πŸ“œ SIMILAR VOLUMES

Effect of midbrain raphe lesion on the a
Effect of midbrain raphe lesion on the antinociceptive action of morphine and other analgesics in rats
✍ R. Samanin; D. Ghezzi; C. Mauron; L. Valzelli πŸ“‚ Article πŸ“… 1973 πŸ› Springer 🌐 English βš– 267 KB

The antinociceptive action of several analgesics was studied by two methods: the hot-plate and the tail compression tests. Lesions of the midbrain raphe, which produce a marked depletion of serotonin in the forebrain, antagonize the analgesic effect of morphine but not that of methadone, meperidine