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Effects of chronic LiCl and RbCl on muricide induced by midbrain raphe lesions in rats

โœ Scribed by Tsuneyuki Yamamoto; Hiroaki Araki; Yoko Abe; Showa Ueki

Book ID
113220173
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
481 KB
Volume
22
Category
Article
ISSN
0091-3057

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Effect of midbrain raphe lesion on the a
Effect of midbrain raphe lesion on the antinociceptive action of morphine and other analgesics in rats
โœ R. Samanin; D. Ghezzi; C. Mauron; L. Valzelli ๐Ÿ“‚ Article ๐Ÿ“… 1973 ๐Ÿ› Springer ๐ŸŒ English โš– 267 KB

The antinociceptive action of several analgesics was studied by two methods: the hot-plate and the tail compression tests. Lesions of the midbrain raphe, which produce a marked depletion of serotonin in the forebrain, antagonize the analgesic effect of morphine but not that of methadone, meperidine