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Leptin induces cyclooxygenase-2 via an interaction with interleukin-1β in the rat brain

✍ Scribed by Wataru Inoue; Stephan Poole; Adrian F. Bristow; Giamal N. Luheshi


Book ID
109025656
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
1001 KB
Volume
24
Category
Article
ISSN
0953-816X

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✍ Victoria Louise Pearson; Nancy Jane Rothwell; Sylvie Toulmond 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 552 KB

Interleukin-1 beta (IL-1␤) has been proposed as a mediator of several forms of brain damage, including that induced by excitotoxins. In vitro studies suggest that glial cells are the effector cells of IL-1␤-mediated neurodegeneration. We have investigated the expression of IL-1␤ protein by glial cel