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Leber's Hereditary Optic Neuropathy: A Case Report

✍ Scribed by Chi-Wu Chang; Chi-Huang Chang; Mei-Lin Peng


Book ID
118649492
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
186 KB
Volume
19
Category
Article
ISSN
0257-5655

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This article reviews the literature on point mutation of mitochondria1 DNA (mtDNA) among Japanese and the authors' research data on pupil reaction in patients with Leber's hereditary optic neuropathy (LHON). Among Japanese, a higher frequency (80-90%) of point mutation at nucleotide position 11778 o