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Leber hereditary optic neuropathy: A nuclear solution of a mitochondrial problem

✍ Scribed by Nils-Göran Larsson


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
51 KB
Volume
52
Category
Article
ISSN
0364-5134

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Leber hereditary optic neuropathy: Does
✍ Chinnery, Patrick F. ;Andrews, Richard M. ;Turnbull, Douglass M. ;Howell, Neil 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB 👁 2 views

Leber hereditary optic neuropathy (LHON) is a major cause of inherited blindness in young males. Approximately 1 in 7 individuals with LHON harbor a mixture of mutated and wild-type (normal) mtDNA (heteroplasmy), and the risks of developing blindness in heteroplasmic LHON individuals are not well ch