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Leber's hereditary optic neuropathy mitochondrial DNA mutations in multiple sclerosis

✍ Scribed by H. Kellar-Wood; N. Robertson; G. G. Govan; D. A. S. Compston; Prof. A. E. Harding


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
447 KB
Volume
36
Category
Article
ISSN
0364-5134

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Visual evoked potentials in Leber's here
✍ Dr. L. J. Dorfman; E. Nikoskelainen; A. R. Rosenthal; R. L. Sogg πŸ“‚ Article πŸ“… 1977 πŸ› John Wiley and Sons 🌐 English βš– 300 KB πŸ‘ 1 views

## Abstract Pattern‐reversal visual evoked potentials (VEPs) were measured serially in two brothers with Leber's hereditary optic neuropathy during the active phase of the disease. VEP latency and configuration were normal prior to the onset of visual symptoms. The earliest abnormalities consisted

Leber hereditary optic neuropathy: Does
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Leber hereditary optic neuropathy (LHON) is a major cause of inherited blindness in young males. Approximately 1 in 7 individuals with LHON harbor a mixture of mutated and wild-type (normal) mtDNA (heteroplasmy), and the risks of developing blindness in heteroplasmic LHON individuals are not well ch