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Latent transforming growth factor-β binding proteins (LTBPs)—structural extracellular matrix proteins for targeting TGF-β action

✍ Scribed by Juha Saharinen; Marko Hyytiäinen; Jussi Taipale; Jorma Keski-Oja

Book ID: 117757868
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 317 KB
Volume: 10
Category: Article
ISSN: 1359-6101
DOI: 10.1016/s1359-6101(99)00010-6

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Recently, the existence of the large latent transforming growth factor ␤ (TGF-␤) complex, consisting of TGF-␤, the N-terminal part of its precursor (latency-associated peptide [LAP]), and the latent TGF-␤ binding protein (LTBP), was demonstrated in rat liver parenchymal cells (PC) and stellate cells