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Sequential deposition of latent TGF-β binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts

✍ Scribed by Katri Koli; Marko Hyytiäinen; Merja J. Ryynänen; Jorma Keski-Oja


Book ID
118506254
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
1020 KB
Volume
310
Category
Article
ISSN
0014-4827

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## Abstract Transforming growth factor (TGF)‐β is secreted and targeted into the extracellular matrix (ECM) in association with one of the latent TGF‐β binding proteins (LTBPs). Activation of these latent complexes is an important regulatory step in TGF‐β signaling. LTBPs target the growth factor i