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Latent membrane protein 1 associated signaling pathways are important in tumor cells of Epstein-Barr virus negative Hodgkin's disease

โœ Scribed by Knecht, Hans; Berger, Christoph; McQuain, Cathy; Rothenberger, Sylvia; Bachmann, Edith; Martin, Jennifer; Esslinger, Christoph; Drexler, Hans G; Cai, Yun C; Quesenberry, Peter J


Book ID
110062543
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
433 KB
Volume
18
Category
Article
ISSN
0950-9232

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## Abstract A large group of juvenile Hodgkin's disease patients (nโ€‰=โ€‰242, mean age 11.7 years, 75% [nโ€‰=โ€‰181] seropositive) was evaluated for antiโ€Epsteinโ€Barr virus (EBV) antibody responses and the presence of EBVโ€encoded EBERโ€RNA and latent membrane proteinโ€1 (LMP1)โ€protein expression in the tumo