Frequent Detection of Epstein-Barr Virus (EBV), EBEB Transcripts and Latent Membrane Protein-1 (LMP-1) in Tumor Cells in Hodgkin's Disease Arising in Childhood
โ Scribed by Kanavaros, P.; Sakalidou, A.; Tzardi, M.; Darivianaki, K.; Delides, G.; Kazlaris, E.; Kalmariti, M.
- Book ID
- 122944388
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 703 KB
- Volume
- 190
- Category
- Article
- ISSN
- 0344-0338
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## Abstract A large group of juvenile Hodgkin's disease patients (nโ=โ242, mean age 11.7 years, 75% [nโ=โ181] seropositive) was evaluated for antiโEpsteinโBarr virus (EBV) antibody responses and the presence of EBVโencoded EBERโRNA and latent membrane proteinโ1 (LMP1)โprotein expression in the tumo
## Abstract There are two types of Epstein Barr virus (EBV): EBVโ1 and EBVโ2, distinguished by genomic polymorphism in the genes encoding the nuclear antigens (EBNAโ2, โ3A, โ3B, โ3C). Latent membrane protein 1 (LMPโ1) is an EBV protein with known oncogenic properties. Different variants had been de