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Latent form of transforming growth factor-β1 acts as a potent growth inhibitor on a human erythroleukemia cell line

✍ Scribed by Yun-Feng Piao; Hidenori Ichijo; Kiyoshi Miyagawa; Hideya Ohashi; Fumimaro Takaku; Kohei Miyazono


Book ID
115763482
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
384 KB
Volume
167
Category
Article
ISSN
0006-291X

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Transforming growth factor β1 (TGF-β1) i
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## Abstract The effects of EGF and TGF‐β1 on the proliferation of 2 ovarian carcinoma cell lines (IGROV1 and OVCCR1) were evaluated. The cell lines were adapted to grow in a restricted serum (0.5%) medium. EGF was required for proliferation of both ovarian cell lines. Low doses of TGF‐β1 inhibited