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Density-Dependent Induction of Apoptosis by Transforming Growth Factor-β1 in a Human Ovarian Carcinoma Cell Line

✍ Scribed by C. Mathieu; S. Jozan; P. Mazars; M.G. Côme; A. Moisand; A. Valette

Book ID
115601914
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
902 KB
Volume
216
Category
Article
ISSN
0014-4827

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Transforming growth factor β1 (TGF-β1) inhibits growth of a human ovarian carcinoma cell line (OVCCR1) and is expressed in human ovarian tumors
✍ S. Jozan; M. Guerrin; P. Mazars; M. Dutaur; B. Monsarrat; F. Cheutin; R. Bugat; 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 French ⚖ 957 KB

## Abstract The effects of EGF and TGF‐β1 on the proliferation of 2 ovarian carcinoma cell lines (IGROV1 and OVCCR1) were evaluated. The cell lines were adapted to grow in a restricted serum (0.5%) medium. EGF was required for proliferation of both ovarian cell lines. Low doses of TGF‐β1 inhibited