Involvement of programmed cell death 4 in transforming growth factor-β1-induced apoptosis in human hepatocellular carcinoma
✍ Scribed by Zhang, H; Ozaki, I; Mizuta, T; Hamajima, H; Yasutake, T; Eguchi, Y; Ideguchi, H; Yamamoto, K; Matsuhashi, S
- Book ID
- 110070653
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 498 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Pleiotrophin (PTN) is a hepatocyte growth factor and considered to play roles in liver fibrogenesis and hepatocarcinogenesis. In this study we examined the mechanism of the action of PTN in these pathological processes. First, we confirmed that hepatic stellate cells (HSCs) and Kupffer
Alteration of transforming growth factor beta1 (TGF-beta1) type II receptor (RII) appears to cause unresponsiveness to TGF-beta1 in tumorigenic cells. Defect in the mononucleotide repeat sequence, i.e., poly A region of TGF-beta1RII gene has been reported to be related to replication error-positive