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Late onset familial Alzheimer's disease: novel presenilin 2 mutation and PS1 E318G polymorphism

✍ Scribed by L. Bernardi; C. Tomaino; M. Anfossi; M. Gallo; S. Geracitano; G. Puccio; R. Colao; F. Frangipane; M. Mirabelli; N. Smirne; R. Giovanni Maletta; A. C. Bruni


Publisher
Springer
Year
2008
Tongue
English
Weight
158 KB
Volume
255
Category
Article
ISSN
0340-5354

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Very early-onset familial Alzheimer's di
✍ Jill S. Goldman; Bruce Reed; Rosalie Gearhart; Joel H. Kramer; Bruce L. Miller πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 47 KB πŸ‘ 1 views

## Background: Early-onset familial alzheimer's disease (eofad) is linked to mutations in three autosomal dominant genes: ps1, ps2 and app. the clinical presentation and age of onset of mutations is variable. ## Objectives: The aim of this report is to describe a novel ps1 mutation believed to be