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The −22c/t polymorphism in presenilin 1 gene is not connected with late-onset and early-onset familial Alzheimer’s disease in Poland

✍ Scribed by C. Żekanowski; D. Religa; K. Safranow; A. Maruszak; V. Dziedziejko; M. Styczyńska; M. Gacia; M. Golan; B. Pepłońska; D. Chlubek; J. Kuźnicki; M. Barcikowska


Publisher
Springer
Year
2004
Tongue
English
Weight
63 KB
Volume
112
Category
Article
ISSN
1435-1463

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Mutations in the presenilin-1 (PS1) gene account for the majority of familial early-onset Alzheimer's disease (EOAD) cases. We screened the coding part of the PS1 gene for the presence of mutations in a French family with EOAD, using single strand conformation polymorphism (SSCP) analysis. Patients