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Lack of evidence for association of Parkin promoter polymorphism (PRKN-258) with increased risk of Parkinson's disease

✍ Scribed by Owen A. Ross; Kristoffer Haugarvoll; Jeremy T. Stone; Michael G. Heckman; Linda R. White; Jan O. Aasly; J. Mark Gibson; Timothy Lynch; Zbigniew K. Wszolek; Ryan J. Uitti; Matthew J. Farrer

Book ID
116820319
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
95 KB
Volume
13
Category
Article
ISSN
1353-8020

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## Abstract Inflammatory events may contribute to the pathogenesis of Parkinson's disease (PD). We conducted a case‐control study in a cohort of 369 PD cases and another cohort of 326 ethnically matched controls to investigate the association of tumor necrosis factor‐α (__TNF‐α__) promoter single n