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Lack of elevated liver carcinogenicity of aminophenylnorharman in p53-deficient mice

โœ Scribed by Takeshi Iidaka; Tetsuya Tsukamoto; Yukari Totsuka; Akihiro Hirata; Hiroki Sakai; Norimitsu Shirai; Masami Yamamoto; Keiji Wakabayashi; Tokuma Yanai; Toshiaki Masegi; Lawrence A. Donehower; Masae Tatematsu


Book ID
116333271
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
475 KB
Volume
217
Category
Article
ISSN
0304-3835

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โœ Uma Santhanam; V. S. Lautha; S. V. Bhide ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 372 KB

The effect of suboptimal levels of dietary vitamin A on diethylnitrosamine (DEN) carcinogenesis was studied in BALE/ c and Swiss mice. Two different dietary regimens were employed to induce vitamin A deficiency and DEN was administered by lavage at 2 dose levels: 0.6 mg/kg as a single dose and 200 m