Three isoenzymes of human carbonic anhydrase (HCA) have been described (designated HCA-I, HCA-I1 and HCA-111). HCA exists as a single polypeptide chain
Lack of effect of cannabinoids on carbonic anhydrase
β Scribed by Dalia Maor; Therese Treves; A. D. Korczyn
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 98 KB
- Volume
- 49
- Category
- Article
- ISSN
- 1435-1463
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## Abstract The molecular size is found to play an important role in carbonic anhydrase (CA) inhibition by sulfonamides. Significant correlation is obtained between the inhibitory power of __meta__βsubstituted analogs and the van der Waals volume (__V__~__w__~) of the substitutents. This provides a
values of the curves m Fig 2 as Ki\_Css/H + 0 These asymptotes are mdicated tn the figure The effect of non-bear adsorptton on the second moment is noted to be large for higher values of KLCJH Also the effect increases as the rate constants (crL and y,,) decrease In principle, plots such as Fig 2 co