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Lack of clastogenic effects in cultured human lymphocytes treated with hydroquinone

✍ Scribed by L. Roza; N. de Vogel; J.H.M. van Delft


Book ID
117450217
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
200 KB
Volume
41
Category
Article
ISSN
0278-6915

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✍ Ü. Egeli; G. Erdogan πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 973 KB

In this study the clastogenic effect of pyrimethamine (Daraprim), a folic acid antagonist used for the treatment of toxoplasmosis and malaria on human chromosomes, was investigated. Pyrimethamine was added to in vitro lymphocyte cultures at six different concentrations: 0.05 (normal therapeutic dose