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Clastogenicity of the fungicide afugan in cultured human lymphocytes

✍ Scribed by Deniz Yüzbaşıoğlu; Mustafa Çelik; Serkan Yılmaz; Fatma Ünal; Hüseyin Aksoy

Book ID
116759088
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
132 KB
Volume
604
Category
Article
ISSN
1383-5718

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The Clastogenic effect of Pyrimethamine
The Clastogenic effect of Pyrimethamine (Daraprim) on human chromosomes in lymphocyte cultures
✍ Ü. Egeli; G. Erdogan 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 973 KB

In this study the clastogenic effect of pyrimethamine (Daraprim), a folic acid antagonist used for the treatment of toxoplasmosis and malaria on human chromosomes, was investigated. Pyrimethamine was added to in vitro lymphocyte cultures at six different concentrations: 0.05 (normal therapeutic dose