Lack of association between schizophrenia and polymorphisms in dopamine metabolism and transport genes
✍ Scribed by Santi Álvarez; Sergi Mas; Patricia Gassó; Miquel Bernardo; Eduard Parellada; Amalia Lafuente
- Book ID
- 111194718
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 212 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0767-3981
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Dopamine transporter (DAT) gene variants do not appear to provide widespread contributions to the etiology of schizophrenia spectrum disorders, according to linkage studies [Persico et al., 1995: Am J Psychiatry 152:134-136]. They may, however, produce modifying effects, more readily detectable in s
Potential contributions of dopamine transporter (DAT) gene variants to delusional disorder were investigated using association analysis. DAT gene VNTR polymorphisms were assessed in 61 delusional patients and 54 normal controls. No differences were found in either genotypic or allelic distributions.