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Labelling of 1-benzyl-1-(3′-dimethylaminopropoxy)-cycloheptane fumarate (active substance of the drug Halidor®) with 14C isotope

✍ Scribed by D. Bánfi; J. Volford; L. Pallos; G. Zólyomi

Publisher
John Wiley and Sons
Year
1971
Tongue
French
Weight
329 KB
Volume
7
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

In order to study the pharmacological properties and mode of action of 1‐benzyl‐1‐(3′‐dimethylaminopropoxy)‐cycloheptane fumarate its labelling was performed with ^14^C. The radioactive carbon has been introduced into the benzyl group and into the dimethylamino moiety of the dimethylaminopropoxy side chain. The chemical and radiochemical purity of the two isotopic isomers was proved by thin layer chromatography and autoradiography.

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