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Potential drugs labelled with 14C. I. The synthesis of 3-benzylamino-5, 6-dihydro-8, 9-dimethoxy-imidazo [5,1-a] isoquinoline hydrochloride

✍ Scribed by G. Zólyomi; E. Koltai; D. Bánfi; K. Harsányi

Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
434 KB
Volume
18
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

3‐Benzylamino‐8, 9‐dimethoxy‐5, 6‐dihydro‐imidazo‐ [5,1‐a] isoquinoline hydrochloride was labelled with ^14^C in two different positions: In one case the ^14^C was built into the position 2 of the imidazole ring, in the other case into the position 3 of the isoquinoline ring. In the first case the mechanism of the halogen‐cyano exchange reaction of 1‐chloromethyl‐5, 6‐dimethoxy‐3, 4‐dihydro‐isoquinoline was investigated by tracer experiments.

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Potential drugs labelled with 14C. II. S
Potential drugs labelled with 14C. II. Synthesis of 1-cyano-3-imino-8, 9-dimethoxy-3, 4,5,6- -tetrahydro-thiazolo[4, 3-a]isoquinoline hydrochloride
✍ E. Koltai; G. Zólyomi; P. Komáromy; D. Bánfi; T. Szüts; K. Takács 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 295 KB

## Abstract The synthesis of 1‐cyano‐3‐imino‐8,9‐dimethoxy‐ ‐3,4, 5,6‐tetrahydro‐thiazolo [4,3‐a]isoquinoline hydrochloride labelled with ^14^C in five different positions: in position 3 (**1a**), in the cyano group at position 1 (**1b**), in position 5 (**1c**), in position 10b (**1d**) and in the