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Labeling Monoclonal Antibodies with 90Yttrium- and 111Indium-DOTA Chelates: A Simple and Efficient Method

✍ Scribed by Li, Min; Meares, Claude F.; Zhong, Gao-Ren; Miers, Laird; Xiong, Cheng-Yi; DeNardo, Sally J.


Book ID
126854692
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
810 KB
Volume
5
Category
Article
ISSN
1043-1802

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Labelling of monoclonal antibodies 10B,
✍ Raymond Reilly; Katherine Sheldon; Alexander Marks; Sylvain Houle πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science βš– 305 KB

Monoclonal antibodies 10B, 8C and M2A were conjugated with cyclic DTPA anhydride to a substitution level of 1 2 mol DTPA/mol antibody. The DTPA-conjugated antibodies were purified by size-exclusion mini-column chromatography and labelled with ["qn]In acetate to a specific activity of 37-74kBq//~g (I