## Chlorination of ~1, @-unsaturated ketones 2a-e at -80°C in THF gives _ rise exclusively to cohaZogenation products 3a-e. The reaction is regiospecific.
La reaction de SIMMONS et les cetones α,β-ethyleniques.
✍ Scribed by Jean-Marie Conia; Jean-Claude Limasset
- Publisher
- Elsevier Science
- Year
- 1965
- Tongue
- French
- Weight
- 212 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Reaction of dimethyl-suZfoxonium metkylide with non-kalogenated a-etkylenic-ketones is known to lead to cycZopropy2 derivatives. With ct-fluoro a-etkylenic-ketones this reaction furnishes fluoro-epoxides, by addition of a metkylene on carbonyl .
Knoevenagel-Cope condensation conditions applied to ketolisation reaction. The Knoevenagel-Cope condensation between acetophenone and ethyl cyanoacetate mainly gives 2-cyano-3-phenyl-but-2-enoic acid ethyl ester and a substituted dihydropyridone as a secondary product. We show that this secondary pr