Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide, reflecting incomplete characterization of underlying mechanisms and lack of early detection. Kru ยจppel-like factor 6 (KLF6) is a ubiquitously expressed zinc finger transcription factor that is deregulated in multiple cancer
โฆ LIBER โฆ
Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer
โ Scribed by Helen L. Reeves; Goutham Narla; Olagunju Ogunbiyi; Asif I. Haq; Amanda Katz; Sharon Benzeno; Eldad Hod; Noam Harpaz; Shlomit Goldberg; Sigal Tal-Kremer; Francis J. Eng; Michael J.P. Arthur; John A. Martignetti; Scott L. Friedman
- Book ID
- 119757584
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 800 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0016-5085
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## Abstract Gliomas are the most common tumors of the central nervous system and have a grave prognosis. Deletion of chromosome 10p15 is one of the most common chromosomal alterations in gliomas. Recently, a candidate tumor suppressor gene, __KLF6__, which is mapped to chromosome 10p, was found to
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